Author

J. E. Pessin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

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Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

G. J. Schwartz· 2 shared C. C. Bastie· 1 shared C. Schmidt· 1 shared C.-T. Lin· 1 shared E. Tarabra· 1 shared E. Yamada· 1 shared H. Kwon· 1 shared H. Zong· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

G. J. Schwartz

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Author profile →

3 papers

Recent·Most cited

The development of hepatic steatosis depends on the presence of liver-innervating parasympathetic cholinergic neurons in mice fed a high-fat diet.

J. Hwang, J. Okada, L. Liu, J. E. Pessin, G. J. Schwartz, Y.-H. Jo

This study shows that parasympathetic cholinergic neurons innervating the liver prevent hepatic steatosis in mice on a high-fat diet by promoting browning of white adipose tissue and altering bile acid metabolism.

bioRxiv · Nov 3, 2023Physiology

Neuronal glucose metabolism sets cholinergic tone and controls thermo-regulated signaling at the neuromuscular junction

Y. Tang, H. Zong, H. Kwon, Y. Qiu, J. B. Pessin, L. Wu, K. A. Buddo, I. Boykov, C. Schmidt, C.-T. Lin, P. D. Neufer, G. J. Schwartz, I. J. Kurland, J. E. Pessin

This study shows that increasing glycolysis in cholinergic neurons boosts acetylcholine levels, reduces blood pressure and heart rate, and improves cold resistance.

eLife · Mar 7, 2022Peer-reviewedCell Biology

Differential activation of Fyn kinase distinguishes saturated and unsaturated fats in mouse macrophages

E. Tarabra, T.-W. A. Lee, V. A. Zammit, M. Vatish, E. Yamada, J. E. Pessin, C. C. Bastie

This study shows that saturated fats activate Fyn kinase in macrophages, leading to nuclear re-localization and oxidative stress, while unsaturated fats do not.

bioRxiv · Jun 29, 2017Cell Biology