Author

P. D. Neufer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1

Frequent Co-Authors

C.-T. Lin· 2 shared S. R. Shaikh· 2 shared A. D'Souza· 1 shared A. E. Al-Shaer· 1 shared A. M. Blee· 1 shared A. Pal· 1 shared A. R. Verkerke· 1 shared C. B. Coleman· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

C.-T. Lin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

XPA tumor variants lead to defects in NER that sensitize cells to cisplatin

A. M. Blee, K. S. Gallagher, H.-S. Kim, M. Kim, C. R. Troll, A. D'Souza, J. Park, P. D. Neufer, O. D. Schärer, W. J. Chazin

This study identifies XPA tumor variants that impair NER, increasing cisplatin sensitivity, and provides mechanistic insights for variant effect prediction.

bioRxiv · Jun 29, 2023Cancer Biology

Neuronal glucose metabolism sets cholinergic tone and controls thermo-regulated signaling at the neuromuscular junction

Y. Tang, H. Zong, H. Kwon, Y. Qiu, J. B. Pessin, L. Wu, K. A. Buddo, I. Boykov, C. Schmidt, C.-T. Lin, P. D. Neufer, G. J. Schwartz, I. J. Kurland, J. E. Pessin

This study shows that increasing glycolysis in cholinergic neurons boosts acetylcholine levels, reduces blood pressure and heart rate, and improves cold resistance.

eLife · Mar 7, 2022Peer-reviewedCell Biology

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

A. Pal, A. E. Al-Shaer, W. Guesdon, M. J. Torres, M. Armstrong, K. Quinn, T. Davis, N. Reisdorph, P. D. Neufer, E. E. Spangenburg, I. Carroll, R. P. Bazinet, G. V. Halade, J. Claria, S. R. Shaikh

This study shows EPA prevents hyperinsulinemia and hyperglycemia via RvE1, which acts through ERV1/ChemR23, and highlights host genetic variation in metabolic responses.

bioRxiv · Mar 31, 2020Biochemistry

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

T. D. Heden, J. M. Johnson, P. J. Ferrara, H. Eshima, A. R. Verkerke, E. J. Wentzler, P. Siripoksup, T. M. Narowski, C. B. Coleman, C.-T. Lin, T. E. Ryan, P. T. Reidy, L. E. de Castro Bras, C. M. Karner, C. F. Burant, , K. Funai

The paper shows that mitochondrial phospholipids, specifically phosphatidylethanolamine (PE), regulate respiratory capacity in skeletal muscle, with PE deficiency causing respiratory failure and oxidative stress.

bioRxiv · Apr 9, 2019Physiology