Author

G. J. Schwartz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 5 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 6 Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. E. Pessin· 2 shared L. Wu· 2 shared N. Lopatinsky· 2 shared R. Nemr· 2 shared S. Higuchi· 2 shared Y. He· 2 shared A. B. Emiliano· 1 shared A. Emiliano· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPhysiology

J. E. Pessin

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Author profile →

6 papers

Recent·Most cited

The development of hepatic steatosis depends on the presence of liver-innervating parasympathetic cholinergic neurons in mice fed a high-fat diet.

J. Hwang, J. Okada, L. Liu, J. E. Pessin, G. J. Schwartz, Y.-H. Jo

This study shows that parasympathetic cholinergic neurons innervating the liver prevent hepatic steatosis in mice on a high-fat diet by promoting browning of white adipose tissue and altering bile acid metabolism.

bioRxiv · Nov 3, 2023Physiology

Neuronal glucose metabolism sets cholinergic tone and controls thermo-regulated signaling at the neuromuscular junction

Y. Tang, H. Zong, H. Kwon, Y. Qiu, J. B. Pessin, L. Wu, K. A. Buddo, I. Boykov, C. Schmidt, C.-T. Lin, P. D. Neufer, G. J. Schwartz, I. J. Kurland, J. E. Pessin

This study shows that increasing glycolysis in cholinergic neurons boosts acetylcholine levels, reduces blood pressure and heart rate, and improves cold resistance.

eLife · Mar 7, 2022Peer-reviewedCell Biology

Fat Mass Regain in Middle-Aged Mice after Sleeve Gastrectomy is divergent from plasma leptin levels

A. Emiliano, Y. He, S. Higuchi, R. Nemr, N. Lopatinsky, G. J. Schwartz

This study shows that middle-aged mice undergoing sleeve gastrectomy experience fat mass regain in the second month post-surgery, while plasma leptin levels remain low.

bioRxiv · Oct 5, 2020 · PreprintPhysiology

Sleeve gastrectomy promotes sustained weight loss while increasing heat production in middle aged, obese female mice

A. B. Emiliano, Y. He, S. Higuchi, N. Lopatinsky, R. Nemr, G. J. Schwartz

This study shows that sleeve gastrectomy in middle-aged obese female mice leads to sustained weight loss and improved glucose tolerance, associated with increased brown adipose tissue metabolism.

bioRxiv · Oct 4, 2020 · PreprintPhysiology

Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue

X. Cui, J. Jing, R. Wu, Q. Cao, F. Li, K. Li, S. Wang, L. Yu, G. J. Schwartz, H. Shi, H. Shi, B. Xue

This study identifies NTF3 as a fat-derived neurotrophic factor that regulates sympathetic innervation and thermogenesis in adipose tissue, influencing energy metabolism and obesity.

bioRxiv · Jun 6, 2020Physiology

Inhibiting the prostaglandin transporter PGT induces non-canonical thermogenesis at thermoneutrality

V. J. Pai, R. Lu, L. Wu, M. Garcia-Macia, W. R. Koba, Y. Chi, R. Singh, G. J. Schwartz, V. L. Schuster

Inhibiting the prostaglandin transporter PGT reduces body fat and induces UCP1-independent thermogenesis in mice on a high-fat diet.

bioRxiv · Nov 9, 2019 · PreprintPhysiology