Author

M. Juhaszova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:metabolism & bioenergetics· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

E. G. Lakatta· 3 shared C. Coletta· 2 shared M. A. Aon· 2 shared R. Bychkov· 2 shared S. J. Sollott· 2 shared A. E. Lyashkov· 1 shared A. Gupta· 1 shared A. J. Silvester· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersPhysiology

E. G. Lakatta

Mutual co-authors in cluster

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4 papers

Recent·Most cited

A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8

K. V. Tarasov, K. Chakir, D. R. Riordon, A. E. Lyashkov, I. Ahmet, M. G. Perino, A. J. Silvester, J. Zhang, M. Wang, Y. O. Lukyanenko, J.-H. Qu, M. C.-R. Barrera, M. Juhaszova, Y. S. Tarasova, B. Ziman, , E. G. Lakatta

This study shows that cardiac-specific overexpression of AC8 in mice leads to adaptive cardiac changes resembling cancer-like survival mechanisms without heart failure.

bioRxiv · May 20, 2022Physiology

The Heart's Pacemaker Mimics Brain Cytoarchitecture and Function: Autonomic innervation, a peripheral glial cell web, and a novel S100B expressing interstitial cell type impart structural and functional complexity to the sinoatrial node

R. Bychkov, M. Juhaszova, M. Calvo-Rubio, L. A. Donald, C. Coletta, K. M. Moorman, S. Tagirova Sirenko, C. Shumaker, A. V. Maltsev, S. J. Sollott, E. G. Lakatta

This study describes the 3D cytoarchitecture of the sinoatrial node, revealing autonomic innervation, peripheral glial cells, and a novel S100B-expressing interstitial cell type that contribute to its structural and functional complexity.

bioRxiv · Feb 4, 2022Physiology

Synchronized cardiac impulses emerge from multi-scale, heterogeneous local calcium signals within and among cells of heart pacemaker tissue

R. Bychkov, M. Juhaszova, K. Tsutsui, C. Coletta, M. D. Stern, V. A. Maltsev, E. G. Lakatta

This study reveals that cardiac action potentials arise from heterogeneous subcellular calcium signals in mouse sinoatrial node tissue, challenging the traditional model of uniform impulse generation.

bioRxiv · Apr 14, 2020Physiology

ATP synthase K+- and H+-flux drive ATP synthesis and enable mitochondrial K+-uniporter function

M. Juhaszova, E. Kobrinsky, D. B. Zorov, B. Nuss, Y. Yaniv, K. W. Fishbein, R. de Cabo, L. Montoliu, S. B. Gabelli, M. A. Aon, S. Cortassa, S. J. Sollott

The paper demonstrates that ATP synthase uses K+ and H+ flux to drive ATP synthesis and functions as a mitochondrial K+-uniporter and KATP-channel.

bioRxiv · Apr 22, 2019 · PreprintBiophysics