Author

K. J. Sastry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Grattoni· 1 shared A. Sizovs· 1 shared B. Nehete· 1 shared C. Y. X. Chua· 1 shared D. Fernandez· 1 shared D. Mirchandani· 1 shared D. Zhou· 1 shared F. P. Pons-Faudoa· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. Grattoni

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Prophylactic and Therapeutic Inhibition of In Vitro SARS-CoV-2 Replication by Oleandrin

K. S. Plante, J. A. Plante, D. Fernandez, D. Mirchandani, N. E. Bopp, P. V. Aguilar, K. J. Sastry, R. A. Newman, S. C. Weaver

This paper tests oleandrin's antiviral activity against SARS-CoV-2 in vitro, showing potent prophylactic and therapeutic effects with high dose reductions in viral production.

bioRxiv · Jul 15, 2020 · PreprintMicrobiology

Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates

F. P. Pons-Faudoa, A. Sizovs, K. A. Shelton, Z. Momin, L. R. Bushman, J. Xu, C. Y. X. Chua, J. E. Nichols, T. Hawkins, J. F. Rooney, M. A. Marzinke, J. T. Kimata, P. L. Anderson, P. N. Nehete, R. C. Arduino, , A. Grattoni

This study evaluates a long-acting tenofovir alafenamide nanofluidic implant in nonhuman primates, showing partial protection against SHIV infection.

bioRxiv · May 13, 2020Bioengineering

Function of ex vivo stimulated Natural killer T cells from patients with chronic HIV-1 infection

P. Thapa, P. Nehete, H. He, B. Nehete, S. Buchl, L. Bull, H. Lu, R. Arduino, K. J. Sastry, D. Zhou

This study shows that NKT cells from HIV-1 infected patients can be expanded and produce antiviral cytokines when stimulated with ex vivo dendritic cells loaded with alpha-galactosylceramide, except in advanced AIDS patients.

bioRxiv · Nov 5, 2019 · PreprintImmunology