Author

N. E. Bopp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1 Organism:virus· 1

Frequent Co-Authors

J. A. Plante· 4 shared K. S. Plante· 3 shared P.-Y. Shi· 3 shared S. C. Weaver· 3 shared V. D. Menachery· 3 shared X. Xie· 3 shared Y. Liu· 3 shared H. Xia· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

J. A. Plante

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.

B. A. Johnson, Y. Zhou, K. G. Lokugamage, M. N. Vu, N. E. Bopp, P. A. Crocquet-Valdes, B. Kalveram, C. Schindewolf, Y. Liu, D. Scharton, J. A. Plante, X. Xie, P. Aguilar, S. Weaver, P.-Y. Shi, , V. D. Menachery

This study shows that mutations in the SARS-CoV-2 nucleocapsid protein enhance viral replication and pathogenesis by increasing phosphorylation and resisting kinase inhibition.

PLOS Pathogens · Jun 21, 2022Peer-reviewedMicrobiology

A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions

Y. Liu, X. Zhang, J. Liu, H. Xia, J. Zou, A. E. Muruato, S. Periasamy, J. A. Plante, N. E. Bopp, C. Kurhade, A. Bukreyev, P. Ren, T. Wang, V. D. Menachery, K. S. Plante, , P.-Y. Shi

This paper describes a live-attenuated SARS-CoV-2 vaccine candidate with deleted ORFs that shows reduced replication and attenuation in animal models, and reports its protective efficacy against wild-type virus challenge.

bioRxiv · Feb 14, 2022Microbiology

A trans-complementation system for SARS-CoV-2

X. Zhang, Y. Liu, J. Liu, A. L. Bailey, K. S. Plante, J. A. Plante, J. Zou, H. Xia, N. E. Bopp, P. V. Aguilar, P. Ren, V. D. Menachery, M. S. Diamond, S. C. Weaver, X. Xie, P.-Y. Shi

This paper develops a trans-complementation system to produce single-round infectious SARS-CoV-2 at BSL-2 labs, enabling safe high-throughput testing without full viral replication.

bioRxiv · Jan 16, 2021 · PreprintMicrobiology

Prophylactic and Therapeutic Inhibition of In Vitro SARS-CoV-2 Replication by Oleandrin

K. S. Plante, J. A. Plante, D. Fernandez, D. Mirchandani, N. E. Bopp, P. V. Aguilar, K. J. Sastry, R. A. Newman, S. C. Weaver

This paper tests oleandrin's antiviral activity against SARS-CoV-2 in vitro, showing potent prophylactic and therapeutic effects with high dose reductions in viral production.

bioRxiv · Jul 15, 2020 · PreprintMicrobiology