Author

K. Kakugawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Cheroutre· 2 shared M. Kronenberg· 2 shared T.-F. Chou· 2 shared A. Nomura· 1 shared A. O. Adegoke· 1 shared C. C. Anderson· 1 shared E. Fedorov· 1 shared G. Thangavelu· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

H. Cheroutre

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Author profile →

3 papers

Recent·Most cited

Internal regulation between constitutively expressed T cell coinhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants

A. O. Adegoke, G. Thangavelu, T.-F. Chou, M. Petersen, K. Kakugawa, J. May, K. Joannou, Q. Wang, K. K. Ellestad, L. Boon, P. A. Bretscher, H. Cheroutre, M. Kronenberg, T. A. Baldwin, C. C. Anderson

This study identifies a regulatory pathway between BTLA and CD5 in T cells that calibrates their expression to establish self-tolerance in recent thymic emigrants.

Open Biology · Oct 30, 2024Peer-reviewedImmunology

Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s.

I. Taniuchi, A. Nomura, M. O. Oishi, T. Kobayashi, W. Seo, K. Kakugawa, S. Muroi, H. Yoshida, T. Endo, K. Moro

The paper identifies a cis-regulatory enhancer critical for Satb1 expression in TH2 cells and activated ILC2s, revealing its role in type 2 immune responses.

bioRxiv · Jan 3, 2023Immunology

HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

W. Liu, T.-F. Chou, S. C. Garrett-Thomson, G.-Y. Seo, E. Fedorov, U. A. Ramagopa, J. B. Bonanno, K. Kakugawa, H. Cheroutre, M. Kronenberg, S. C. Almo

The paper determines HVEM structures and generates mutants to reveal distinct functions of binding to LIGHT and BTLA/CD160 in immune responses.

bioRxiv · Jun 16, 2021Immunology