Author

J. B. Bonanno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1 Organism:Xenopus· 1

Frequent Co-Authors

S. C. Almo· 4 shared S. C. Garrett-Thomson· 2 shared A. B. Massimi· 1 shared A. Celikgil· 1 shared A. J. Noble· 1 shared A. Mengotto· 1 shared A. S. Wirchniaski· 1 shared a. Sali· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersBiochemistry

S. C. Almo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Unique Binding and Stabilization Mechanisms Employed By and Engineered Into Nanobodies.

N. E. Ketaren, P. C. Fridy, V. Malashkevich, T. Sanyal, M. Brilliantes, M. K. Thompson, D. A. Orens, J. B. Bonanno, a. Sali, S. C. Almo, B. T. Chait, M. P. Rout

This study identifies mechanisms enabling nanobodies to bind antigens with high affinity and stability, revealing a conserved region critical for their function and suggesting strategies for their optimization.

bioRxiv · Oct 22, 2023 · PreprintBiochemistry

HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

W. Liu, T.-F. Chou, S. C. Garrett-Thomson, G.-Y. Seo, E. Fedorov, U. A. Ramagopa, J. B. Bonanno, K. Kakugawa, H. Cheroutre, M. Kronenberg, S. C. Almo

The paper determines HVEM structures and generates mutants to reveal distinct functions of binding to LIGHT and BTLA/CD160 in immune responses.

bioRxiv · Jun 16, 2021Immunology

Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis

N. G. Herrera, N. C. Morano, A. Celikgil, G. I. Georgiev, R. J. Malonis, J. H. Lee, K. Tong, O. Vergnolle, A. B. Massimi, L. Y. Yen, A. J. Noble, M. Kopylov, J. B. Bonanno, S. C. Garrett-Thomson, D. B. Hayes, , S. C. Almo

This study evaluates the production, characterization, and antigenicity of SARS-CoV-2 S protein constructs in two cell lines, showing high-quality yields and consistent behavior across assays.

bioRxiv · Jun 14, 2020Biochemistry

Structure of a Single Chain H2A/H2B Dimer

C. Warren, J. B. Bonanno, S. C. Almo, D. Shechter

The paper creates a single-chain H2A/H2B dimer and determines its structure, showing it resembles nucleosomal H2A/H2B, providing a tool for studying H2A/H2B-interacting proteins.

bioRxiv · Mar 15, 2020Biochemistry