Author

H. Cheroutre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. Kronenberg· 4 shared G.-Y. Seo· 3 shared K. Kakugawa· 2 shared Q. Wang· 2 shared T.-F. Chou· 2 shared A. Chawla· 1 shared A. L. R. Premlal· 1 shared A. O. Adegoke· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

M. Kronenberg

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Author profile →

4 papers

Recent·Most cited

Internal regulation between constitutively expressed T cell coinhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants

A. O. Adegoke, G. Thangavelu, T.-F. Chou, M. Petersen, K. Kakugawa, J. May, K. Joannou, Q. Wang, K. K. Ellestad, L. Boon, P. A. Bretscher, H. Cheroutre, M. Kronenberg, T. A. Baldwin, C. C. Anderson

This study identifies a regulatory pathway between BTLA and CD5 in T cells that calibrates their expression to establish self-tolerance in recent thymic emigrants.

Open Biology · Oct 30, 2024Peer-reviewedImmunology

Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity

S. Chandra, G. Ascui, T. Riffelmacher, A. Chawla, C. Ramirez-Suastegui, V. C. Castelan, G. Seumois, H. Simon, M. P. Murray, G.-Y. Seo, A. L. R. Premlal, G. Verstichel, Y. Li, C.-H. Lin, J. Greenbaum, , M. Kronenberg

This study identifies MAIT cell heterogeneity in mice and humans through single-cell RNA sequencing and metabolic analysis, revealing distinct transcriptomes and metabolic states in different tissues and species.

bioRxiv · Dec 20, 2021 · PreprintImmunology

HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

W. Liu, T.-F. Chou, S. C. Garrett-Thomson, G.-Y. Seo, E. Fedorov, U. A. Ramagopa, J. B. Bonanno, K. Kakugawa, H. Cheroutre, M. Kronenberg, S. C. Almo

The paper determines HVEM structures and generates mutants to reveal distinct functions of binding to LIGHT and BTLA/CD160 in immune responses.

bioRxiv · Jun 16, 2021Immunology

Epithelial HVEM promotes basement membrane synthesis and intraepithelial T cell survival and migration

D. Takahashi, Q. Wang, G.-Y. Seo, J.-W. Shui, Z. Mikulski, P. Marcovecchio, M. Takahashi, C. D. Surh, H. Cheroutre, M. Kronenberg

This study shows that epithelial HVEM supports basement membrane synthesis and IET survival and migration in the intestine.

bioRxiv · Sep 30, 2020 · PreprintImmunology