Author

K. Kasahara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Microbiology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

H. Nakamura· 2 shared I. Fukuda· 2 shared J. Higo· 2 shared N. Kamiya· 2 shared S. Sakuraba· 2 shared Y. Fukunishi· 2 shared A. J. Lusis· 1 shared A. Kusaka· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBiophysics

H. Nakamura

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Foam rolling intervention improves lactate clearance after high-intensity exercise

K. Kasahara, K. Oneyama, T. Ito, M. Nakamura, G. Ochi

This study investigates whether foam rolling improves lactate clearance and cognitive recovery after high-intensity exercise, finding reduced lactate levels and partial executive function recovery.

Sports · Nov 8, 2024Peer-reviewedPhysiology

Gut bacteria impact host uric acid burden and its association with atherosclerosis

K. Kasahara, R. L. Kerby, Q. Zhang, M. Pradhan, M. Mehrabian, A. J. Lusis, G. Bergstrom, F. Backhed, F. E. Rey

This study shows gut bacteria influence uric acid levels and atherosclerosis in mice and humans by catabolizing purines.

bioRxiv · Dec 12, 2022 · PreprintMicrobiology

Fly-casting with ligand-sliding and orientational selection to support the complex formation of a GPCR and a middle-sized flexible molecule

J. Higo, K. Kasahara, G.-J. Bekker, B. Ma, S. Sakuraba, S. Iida, N. Kamiya, I. Fukuda, H. Kono, Y. Fukunishi, H. Nakamura

This paper uses a computational method to simulate the binding mechanism of bosentan to hETB, identifying key steps like fly-casting and ligand-sliding.

bioRxiv · Feb 28, 2022 · PreprintBiophysics

Modeling the SARS-CoV-2 nsp1--5'-UTR complex via extended ensemble simulations

S. Sakuraba, X. Qilin, K. Kasahara

This study uses molecular dynamics simulations to investigate how SARS-CoV-2 RNA evades nsp1-mediated host translation shutoff by interacting with specific regions of nsp1.

bioRxiv · Feb 24, 2021Biophysics

Molecular interaction mechanism of a 14-3-3 protein with a phosphorylated peptide elucidated by enhanced conformational sampling

J. Higo, T. Kawabata, A. Kusaka, K. Kasahara, N. Kamiya, I. Fukuda, K. Mori, Y. Hata, Y. Fukunishi, H. Nakamura

This paper uses enhanced conformational sampling to study the binding mechanism of a phosphorylated peptide to a 14-3-3 protein, identifying stable clusters and a phosphorylation-dependent binding process.

bioRxiv · May 24, 2020Biophysics

Inoculum size effects in blaIMP-6 and plasmid-mediated quinolone resistance gene-positive Enterobacteriaceae in Japan

Y. Ogawa, R. Nakano, K. Kasahara, T. Mizuno, N. Hirai, A. Nakano, Y. Suzuki, N. Kakuta, T. Masui, H. Yano, K. Mikasa

This study examines resistance genes and inoculum size effects in IMP-6 MBL-producing Enterobacteriaceae with reduced susceptibility to fluoroquinolones and amikacin in Japan.

bioRxiv · Jan 30, 2019 · PreprintMicrobiology