Author
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2 papers
Recent·Most cited
M. Y. Szeto, A. Mase, K. Kulhanek, S. Banerjee, I. Rubio, J. Roose, N. P. Shah
This study identifies PLCG1 as a mediator of RAS activation by BCR-ABL1 and FLT3-ITD, showing that PLCG1 inhibition enhances sensitivity to TKIs in CML and AML.
bioRxiv · Apr 7, 2023 · PreprintCancer Biology
M. Baars, T. Douma, D. R. Simeonov, D. R. Myers, S. Banerjee, K. Kulhanek, S. Zwakenberg, M. P. Baltissen, S. de Roock, F. van Wijk, M. Vermeulen, A. Marson, J. P. Roose, Y. Vercoulen
The paper shows that reduced RASGRP1 expression, regulated by RUNX1, contributes to autoimmunity by impairing T cell function and increasing inflammation.
bioRxiv · Nov 8, 2019Immunology