K. Lee

This paper introduces a rapid antimicrobial susceptibility test using laser speckle dynamics to detect bacterial growth in 2-4.5 hours.

The paper shows that air mass origin affects airborne microbial diversity at the Great Barrier Reef, with oceanic and continental trajectories influencing bacterial and fungal composition.

The paper performs single-cell RNA sequencing on TNBC tumors to identify novel immune cell subsets and their associations with survival and TCR signaling.

This study identifies molecular mechanisms by which Streptococcus A12 competes with S. mutans using functional genomics and gene deletion analysis.

This study shows DEHP alters gut microbiota composition and metabolite profiles in mice, increasing p-cresol and decreasing butyrate, linked to neurodevelopmental disorders.

The paper introduces EMMA, a computational workflow for untargeted metabolomics annotation, increasing candidate set size and identifying novel metabolites in CHO cells and murine cecal microbiota.

The paper introduces multi-ATOM, a high-throughput QPI method that enables subcellular resolution and accurate cell-type classification without compromising speed or quality.

This paper introduces a deep learning method for label-free cell nucleus segmentation in time-lapse refractive index tomograms, validated across multiple experiments.

This paper develops a deep transfer learning method to classify LDIH holograms without image reconstruction, enabling low-cost point-of-care diagnostics.

The paper analyzes genetic diversity in soybean to determine domestication origin and identify loci associated with domestication traits.

This paper introduces HACKS, a machine learning framework to analyze live cell imaging data and uncover subcellular protrusion heterogeneity and actin regulator dynamics.

This study evolves CRISPR-Cas9 to enhance specificity while maintaining on-target activity in human cells.

The paper shows that aged hematopoietic stem cells exhibit a myeloid-biased transcriptional response to inflammation, which is linked to Klf5, Ikzf1, and Stat3.

The paper presents two cryo-EM structures of the human KATP channel complexed with ATP and ADP, revealing their roles in channel regulation.

This study shows that miR-128 inhibits HIV-1 replication by targeting TNPO3 mRNA, reducing its expression and affecting viral spread.