Author

K. M. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Genetic & Genomic Medicine· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Droop· 1 shared A. K. Jochmans· 1 shared A. Trower· 1 shared C. Castaneda-Garcia· 1 shared C. D. Robles-Espinoza· 1 shared C. E. Patterson· 1 shared D. J. Adams· 1 shared D. T. Bishop· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

A. Droop

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

H. Dong, J. Yang, K. He, W.-B. Zheng, D.-H. Lai, J. Liu, H.-Y. Ding, R.-B. Wu, K. M. Brown, G. Hide, Z.-R. Lun, X.-Q. Zhu, S. Long

This study identifies apicoplast transporters in Toxoplasma gondii using TurboID and genome engineering, showing AMT1 and AMT2 are critical for parasite growth and virulence.

bioRxiv · Jun 6, 2023 · PreprintMicrobiology

LEADER (Leaf Element Accumulation from Deep Roots): a nondestructive phenotyping platform to estimate rooting depth in the field

M. T. Hanlon, K. M. Brown, J. P. Lynch

LEADER estimates maize root depth using leaf elemental content analysis, achieving high accuracy in field sites and demonstrating potential for broader application.

bioRxiv · May 2, 2023Plant Biology

Functional Analysis of the Expanded Phosphodiesterase Gene Family in Toxoplasma gondii Tachyzoites

W. J. Moss, C. E. Patterson, A. K. Jochmans, K. M. Brown

This study identifies TgPDE1 and TgPDE2 as key regulators of cyclic nucleotide levels in Toxoplasma gondii tachyzoites, affecting motility and growth through distinct functions.

bioRxiv · Sep 21, 2021Microbiology

Fine-mapping of melanoma-associated genomic regions identifies novel causal SNPs in the MTAP/CDKN2A and CASP8 loci

C. Castaneda-Garcia, V. Iyer, J. Nsengimana, A. Trower, A. Droop, K. M. Brown, J. Choi, T. Zhang, M. Harland, J. A. Newton-Bishop, D. T. Bishop, D. J. Adams, M. M. Iles, C. D. Robles-Espinoza

The paper fine-maps melanoma-associated genomic regions to identify novel causal SNPs in the MTAP/CDKN2A and CASP8 loci using sequencing, variant filtering, and functional assays.

medRxiv · Jul 17, 2021 · PreprintGenetic & Genomic Medicine

Toxoplasma bradyzoites exhibit physiological plasticity of calcium and energy stores controlling motility and egress.

Y. Fu, K. M. Brown, N. G. Jones, S. N. J. Moreno, L. D. Sibley

This study shows that Toxoplasma bradyzoites have reduced calcium and energy stores, limiting their motility and egress, but they can rapidly restore these stores upon release from cysts.

bioRxiv · May 17, 2021Microbiology