Author

V. Iyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. J. Adams· 2 shared A. A. Hyman· 1 shared A. Chhabra· 1 shared A. Dashi· 1 shared A. Droop· 1 shared A. O. Speak· 1 shared A. Rapp· 1 shared A. Swiatkowska· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

D. J. Adams

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Author profile →

5 papers

Recent·Most cited

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

S. Maharana, S. Kretschmer, S. Hunger, X. Yan, D. Kuster, S. Traikov, T. Zillinger, N. Chappidi, N. Lucas, K. I. Maser, H. Maatz, A. Rapp, V. Marchand, V. Iyer, A. Chhabra, , M. A. Lee-Kirsch

This study shows SAMHD1 regulates innate immunity by controlling RNA condensation, preventing immune recognition of self RNA and reducing inflammation.

bioRxiv · Jul 12, 2022Immunology

Fine-mapping of melanoma-associated genomic regions identifies novel causal SNPs in the MTAP/CDKN2A and CASP8 loci

C. Castaneda-Garcia, V. Iyer, J. Nsengimana, A. Trower, A. Droop, K. M. Brown, J. Choi, T. Zhang, M. Harland, J. A. Newton-Bishop, D. T. Bishop, D. J. Adams, M. M. Iles, C. D. Robles-Espinoza

The paper fine-maps melanoma-associated genomic regions to identify novel causal SNPs in the MTAP/CDKN2A and CASP8 loci using sequencing, variant filtering, and functional assays.

medRxiv · Jul 17, 2021 · PreprintGenetic & Genomic Medicine

Long noncoding RNA VENTHEART is required for cardiomyocyte specification and function

A. Dashi, T. W. Lek Wen, G. Anene, B. Pan, M. I. Autio, Z. Tiang, R. Hartman, J. Stenzig, H. Wei, G. Chen, M. Ackers-Johnson, B. Lim, A. Walentinsson, V. Iyer, M. Jonsson, R. Foo

This study identifies VENTHEART as a lncRNA essential for cardiomyocyte specification, maturation, and function, with potential relevance to heart disease.

bioRxiv · Feb 1, 2021 · PreprintCell Biology

A genome-wide screen in mice to identify cell-extrinsic regulators of pulmonary metastatic colonisation

L. van der Weyden, A. Swiatkowska, V. Iyer, A. O. Speak, D. J. Adams

The paper identifies 34 genes that regulate pulmonary metastatic colonisation in mice through a genome-wide screen using mutant mice and metastatic melanoma cells.

bioRxiv · Feb 10, 2020Cancer Biology

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

V. Iyer, K. Boroviak, M. Thomas, B. Doe, E. Ryder, D. Adams

The paper assesses CRISPR-Cas9 off-target effects in gene-edited mice using trio sequencing and finds no unexpected off-target activity.

bioRxiv · Feb 9, 2018Bioengineering