Author

K. Mahdaviani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

M. Liesa· 2 shared O. S. Shirihai· 2 shared A. Chen· 1 shared A. E. Jones· 1 shared A. Petcherski· 1 shared A. S. Divakaruni· 1 shared B. E. Corkey· 1 shared B. R. Desousa· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCell Biology

M. Liesa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease

N. Jafari, A. Chen, M. Kolla, I. R. Pompa, Y. Qiu, R. Yu, P. Llevenes, C. S. Ennis, J. Mori, K. Mahdaviani, M. Halpin, G. A. Gignac, C. M. Heaphy, S. Monti, G. V. Denis

This study identifies plasma exosomal miRNAs associated with T2D that induce EMT and immune checkpoint expression in prostate cancer cells.

bioRxiv · Feb 1, 2022Cancer Biology

High-Throughput Image Analysis of Lipid-Droplet-Bound Mitochondria

N. Miller, D. Wolf, N. Alsabeeh, K. Mahdaviani, M. Segawa, M. Liesa, O. S. Shirihai

The paper introduces a machine learning method to segment mitochondria in BAT images, revealing differences in H2O2 production between cytosolic and peri-droplet mitochondria.

bioRxiv · Mar 10, 2020 · PreprintCell Biology

Blocking mitochondrial pyruvate import causes energy wasting via futile lipid cycling in brown fat

M. Veliova, C. Mendes Ferreira, I. Y. Benador, A. E. Jones, B. R. Desousa, K. Mahdaviani, R. Acin-Perez, A. Petcherski, A. S. Divakaruni, M. Prentki, B. E. Corkey, M. Liesa, M. F. Oliveira, O. S. Shirihai

The paper shows that blocking mitochondrial pyruvate import increases ATP synthesis via futile lipid cycling in brown adipocytes, enhancing energy expenditure without adrenergic stimulation.

bioRxiv · Nov 15, 2019 · PreprintBiochemistry