Author

K. Monahan

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Cell Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Stavros LomvardasiD· 3 shared A. Horta· 2 shared A. Dagenais· 1 shared A. J. Robison· 1 shared A. R. Hemnes· 1 shared A.M. Mumbay-Wafula· 1 shared Alice Mumbey-Wafula· 1 shared C. S. Moore· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersGenomics

Stavros LomvardasORCID

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Author profile →

5 papers

Recent·Most cited

Interleukin-10-producing monocytes contribute to sex differences in pain resolution in mice and humans.

J. Sim, E. O'Guin, K. Monahan, C. Sugimoto, S. McLean, L. Albertorio-Saez, Y. Zhao, A. Dagenais, S. Laumet, M. Bernard, J. K. Folger, A. J. Robison, S. D. Linnstaedt, G. Laumet

The paper shows that male mice and humans have higher IL-10-producing monocytes, which correlate with faster pain resolution, and that androgens drive this sex difference.

bioRxiv · Nov 3, 2023Immunology

Myeloid Cell-Derived IL1β Contributes to Pulmonary Vascular Remodeling in Heart Failure with Preserved Ejection Fraction

V. Agrawal, J. A. Kropski, J. J. Gokey, E. Kobeck, M. B. Murphy, K. T. Murray, N. L. Fortune, C. S. Moore, D. F. Meoli, K. Monahan, Y. R. Su, T. Blackwell, D. K. Gupta, M. H. Talati, E. J. Carrier, , A. R. Hemnes

This study identifies myeloid cell-derived IL1β as a key driver of pulmonary vascular remodeling in HFpEF using a murine model and multi-omics approaches.

bioRxiv · May 18, 2023 · PreprintCell Biology

Ldb1 mediates trans enhancement in mammals

K. Monahan, A. Horta, A.M. Mumbay-Wafula, Lei Li, Yingdong Zhao, Paul E. Love, Stavros Lomvardas

The paper shows that Ldb1 facilitates trans interactions between enhancers in olfactory receptor gene expression, supporting trans enhancement as a mechanism for mammalian gene activation.

bioRxiv · Mar 23, 2018 · PreprintGenomics

Cell type-specific interchromosomal interactions as a mechanism for transcriptional diversity

A. Horta, K. Monahan, Elizaveta Bashkirova, Stavros Lomvardas

The paper identifies interchromosomal interactions in mouse olfactory sensory neurons that support stochastic gene expression during differentiation.

bioRxiv · Mar 23, 2018 · PreprintGenomics

Cooperative Interactions Enable Singular Olfactory Receptor Expression

K. Monahan, Ira Schieren, Jonah Cheung, Alice Mumbey-Wafula, Edwin S. Monuki, Stavros Lomvardas

The paper shows that cooperative transcription factors Lhx2 and Ebf specify olfactory receptor enhancers, enabling singular OR expression through interchromosomal interactions.

eLife · Sep 17, 2017Peer-reviewedNeuroscience