Author

J. J. Gokey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. A. Kropski· 5 shared T. S. Blackwell· 3 shared A. S. McCall· 2 shared C. J. Taylor· 2 shared C. L. Calvi· 2 shared D. S. Nichols· 2 shared J. D. West· 2 shared S. S. Gutor· 2 shared

Activity by Year

2021-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersCell Biology

J. A. Kropski

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Hypoxia-inducible factor-2 (HIF2) regulates alveolar regeneration after repetitive injury

A. S. McCall, H. Tanjore, A. Burman, T. Sherrill, M. Chapman, C. L. Calvi, J. Camarata, R. P. Hunt, D. Nichols, N. Banovich, W. E. Lawson, J. J. Gokey, J. A. Kropski, T. S. Blackwell

Inhibiting hypoxia-inducible-factor 2 (HIF2) promotes functional lung alveolar epithelial repair following recurrent injury.

bioRxiv · Sep 17, 2023 · PreprintCell Biology

Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury

G. T. DiGiovanni, W. Han, T. Sherrill, C. J. Taylor, D. S. Nichols, N. M. Geis, U. K. Singha, C. L. Calvi, A. S. McCall, M. M. Dixon, Y. Lui, J.-H. Jang, S. S. Gutor, V. V. Polosukhin, T. S. Blackwell, , J. J. Gokey

This study shows that Yap/Taz in AT2 cells are essential for alveolar regeneration and preventing fibrosis after lung injury.

bioRxiv · Jun 22, 2023Cell Biology

Dysregulated alveolar epithelial cell progenitor function and identity in Hermansky-Pudlak syndrome

J. Y. Wang, N. S. Michki, S. Sitaraman, B. J. Banaschewski, R. Jamal, J. J. Gokey, S. M. Lin, J. B. Katzen, M. C. Basil, E. Cantu, J. A. Kropski, J. A. Zepp, D. B. Frank, L. R. Young

This study identifies intrinsic AT2 progenitor dysfunction and p53 pathway dysregulation as novel mechanisms driving pulmonary fibrosis in Hermansky-Pudlak syndrome.

bioRxiv · Jun 17, 2023Cell Biology

Myeloid Cell-Derived IL1β Contributes to Pulmonary Vascular Remodeling in Heart Failure with Preserved Ejection Fraction

V. Agrawal, J. A. Kropski, J. J. Gokey, E. Kobeck, M. B. Murphy, K. T. Murray, N. L. Fortune, C. S. Moore, D. F. Meoli, K. Monahan, Y. R. Su, T. Blackwell, D. K. Gupta, M. H. Talati, E. J. Carrier, , A. R. Hemnes

This study identifies myeloid cell-derived IL1β as a key driver of pulmonary vascular remodeling in HFpEF using a murine model and multi-omics approaches.

bioRxiv · May 18, 2023 · PreprintCell Biology

Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome

S. S. Gutor, R. I. Salinas, D. S. Nichols, J. M. R. Bazzano, W. Han, J. J. Gokey, G. Vasiukov, J. D. West, D. C. Newcomb, A. E. Dikalova, B. W. Richmond, S. I. Dikalov, T. S. Blackwell, V. V. Polosukhin

This study develops a mouse model of repetitive sulfur dioxide exposure that mimics post-deployment respiratory syndrome features, identifying oxidative stress as a mediator of pulmonary vascular disease.

bioRxiv · May 15, 2023Pathology

Single-cell transcriptomic assessment of cellular phenotype stability in human precision-cut lung slices

N. I. Winters, C. J. Taylor, C. S. Jetter, J. E. Camarata, A. J. Gutierrez, L. T. Bui, J. J. Gokey, M. Bacchetta, N. E. Banovich, J. M. S. Sucre, J. A. Kropski

The paper compares single-cell transcriptomic profiles of human PCLS after five days of culture to freshly isolated lung tissue, finding changes in endothelial and alveolar epithelial cell programs but stable immune cell profiles.

bioRxiv · Aug 19, 2021 · PreprintCell Biology