Author

K. Parapatics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

K. L. Bennett· 3 shared A. Ringler· 2 shared C. Bock· 2 shared P. Majek· 2 shared S. Kubicek· 2 shared S. Sdelci· 2 shared A. Bergthaler· 1 shared A. C. Mueller· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

K. L. Bennett

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects

R. Ghose, F. Pezzano, S. Kourtis, I. Sheraj, S. Das, A. Ganez-Zapater, U. Ghose, L. Espinar, K. Parapatics, V. Venturini, A. C. Muller, V. Ruprecht, S. Sdelci

This study shows that mechanical confinement causes mitochondria to relocate to the nucleus, leading to a nuclear ATP surge that supports DNA repair and cell cycle progression.

bioRxiv · Dec 20, 2023Cell Biology

MICS1 is the Ca2+ /H+ antiporter of mammalian mitochondria

S. Austin, R. Mekis, S. E. M. Mohammed, M. Scalise, C. Pfeiffer, M. Galluccio, T. Borovec, K. Parapatics, D. Vitko, N. Dinhopl, K. L. Bennett, K. Nowikovsky

The paper identifies MICS1 as the mitochondrial Ca2+/H+ antiporter, resolving a long-standing gap in understanding mitochondrial Ca2+ transport.

bioRxiv · Nov 11, 2021 · PreprintBiochemistry

Biomolecular Condensation Drives Leukemia Caused by NUP98-Fusion Proteins

S. Terlecki-Zaniewicz, T. Eder, J. Schmoellerl, T. Humer, N. Kuchynka, K. Parapatics, E. Heyes, F. G. Liberante, A. C. Müller, F. Grebien

This study identifies biomolecular condensation as a mechanism by which NUP98-fusion proteins drive leukemia by altering condensate composition and gene regulation.

bioRxiv · Nov 16, 2020 · PreprintCancer Biology

MTHFD1 is a genetic interactor of BRD4 and links folate metabolism to transcriptional regulation

S. Sdelci, A. Rendeiro, P. Rathert, G. Hofstaetter, A. Ringler, H. P. Moll, W. You, K. Klavins, B. Guertl, M. Farlik, S. Schick, F. Klepsch, M. Oldach, P. Buphamalai, F. Schischlik, , S. Kubicek

This study identifies MTHFD1 as a genetic and physical interactor of BRD4, linking folate metabolism to transcriptional regulation and showing synergistic effects on cancer cell viability.

bioRxiv · Oct 10, 2018Cancer Biology

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

L. Kosack, B. Wingelhofer, A. Popa, B. Vilagos, A. Orlova, P. Majek, K. Parapatics, A. Lercher, B. Agerer, A. Ringler, J. Klughammer, M. Smyth, K. Khamina, H. Baazim, D. A. Rosa, , A. Bergthaler

This study identifies the ERBB-STAT3 axis as a driver of Tasmanian devil facial tumor disease and proposes a dual chemo-immunotherapeutic strategy.

bioRxiv · Apr 12, 2018Cancer Biology