Author

F. Pezzano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

V. Ruprecht· 4 shared A. Ganez-Zapater· 2 shared L. Espinar· 2 shared M. Krieg· 2 shared R. Ghose· 2 shared S. Das· 2 shared S. Jimenez-Delgado· 2 shared S. Sdelci· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCell Biology

V. Ruprecht

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects

R. Ghose, F. Pezzano, S. Kourtis, I. Sheraj, S. Das, A. Ganez-Zapater, U. Ghose, L. Espinar, K. Parapatics, V. Venturini, A. C. Muller, V. Ruprecht, S. Sdelci

This study shows that mechanical confinement causes mitochondria to relocate to the nucleus, leading to a nuclear ATP surge that supports DNA repair and cell cycle progression.

bioRxiv · Dec 20, 2023Cell Biology

Adaptation to ARF6-depletion in KRAS-driven PDAC is abolished by targeting TLR2

R. Ghose, S. Das, J. Urgel-Solas, F. Pezzano, D. Datta, U. Ghose, A. Ganez-Zapater, N. Pardo-Lorente, L. Espinar, L. Garcia, C. Cannata, V. Ruprecht, A. Janic, S. Sdelci

This study identifies TLR2 as a target to counteract adaptation to ARF6 depletion in KRAS-driven PDAC, reducing proliferation, migration, and invasion.

bioRxiv · Nov 30, 2023 · PreprintCancer Biology

Measuring age-dependent viscoelastic properties of organelles, cells and organisms via Time-Shared Optical TweezerMicrorheology

F. Catala-Castro, S. Ortiz-Vasquez, C. Martinez-Fernandez, F. Pezzano, C. Garcia-Cabau, M. Fernandez-Campo, N. Sanfeliu-Cerdan, S. Jimenez-Delgado, X. Salvatella, V. Ruprecht, P. A. Frigeri, M. Krieg

This paper introduces a time-shared optical tweezer microrheology method to measure age-dependent viscoelastic properties of biological materials, demonstrating its application in biomolecular condensates, zebrafish cells, and C. elegans.

bioRxiv · Oct 17, 2023 · PreprintBiophysics

The nucleus measures shape deformation for cellular proprioception and regulates adaptive morphodynamics

V. Venturini, F. Pezzano, F. Catala Castro, H.-M. Häkkinen, S. Jimenez-Delgado, M. Colomer-Rosell, M. Marro Sanchez, Q. Tolosa-Ramon, S. Paz-Lopez, M. A. Valverde, P. Loza-Alvarez, M. Krieg, S. Wieser, V. Ruprecht

The paper shows the nucleus acts as a shape deformation sensor, enabling cells to adapt behavior to their microenvironment through calcium-dependent mechano-transduction.

bioRxiv · Dec 5, 2019 · PreprintCell Biology