Author

K. Pflug

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. P. West· 1 shared B. R. Hoffmann· 1 shared C. G. Martinez· 1 shared C. L. Cannon· 1 shared J. J. VanPortfliet· 1 shared J. Wong· 1 shared M. Ramanathan· 1 shared P. J. McGuire· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. P. West

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1 paper

Recent·Most cited

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease

J. J. VanPortfliet, Y. Lei, M. Ramanathan, C. G. Martinez, J. Wong, T. J. Stodola, B. R. Hoffmann, K. Pflug, R. Sitcheran, S. C. Kneeland, S. A. Murray, P. J. McGuire, C. L. Cannon, A. P. West

This study identifies caspase-11 as a driver of macrophage hyperinflammation in Polg-related mitochondrial disease models, linking IFN-I signaling to exacerbated infection outcomes.

bioRxiv · May 11, 2024Immunology