Author

C. L. Cannon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

K. N. Shah· 2 shared Q. Chen· 2 shared A. P. West· 1 shared A. R. Mullen· 1 shared B. Chirra· 1 shared B. R. Hoffmann· 1 shared C. G. Martinez· 1 shared J. J. VanPortfliet· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

K. N. Shah

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease

J. J. VanPortfliet, Y. Lei, M. Ramanathan, C. G. Martinez, J. Wong, T. J. Stodola, B. R. Hoffmann, K. Pflug, R. Sitcheran, S. C. Kneeland, S. A. Murray, P. J. McGuire, C. L. Cannon, A. P. West

This study identifies caspase-11 as a driver of macrophage hyperinflammation in Polg-related mitochondrial disease models, linking IFN-I signaling to exacerbated infection outcomes.

bioRxiv · May 11, 2024Immunology

Antimicrobial Effects of Ibuprofen Combined with Standard of Care Antimicrobials against Cystic Fibrosis Pathogens

Q. Chen, M. Ilanga, S. B. Simbassa, B. Chirra, K. N. Shah, C. L. Cannon

This study investigates the antimicrobial synergy between ibuprofen and standard-of-care antibiotics against CF pathogens, showing in vitro and in vivo efficacy against drug-resistant strains.

bioRxiv · May 11, 2021 · PreprintMicrobiology

N-Acetyl Cysteine Abrogates Silver-Induced Reactive Oxygen Species in Human Cells Without Altering Silver-Based Antimicrobial Activity

K. N. Shah, P. N. Shah, A. R. Mullen, Q. Chen, R. DeBerardinis, C. L. Cannon

This study shows N-acetyl cysteine (NAC) reduces silver-induced reactive oxygen species (ROS) in human cells without affecting silver's antimicrobial activity.

bioRxiv · Oct 3, 2019Pharmacology & Toxicology