Author

B. R. Hoffmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

T. J. Stodola· 2 shared A. P. West· 1 shared A. S. Greene· 1 shared A. W. Cowley· 1 shared C. G. Martinez· 1 shared C. J. Brunton· 1 shared C. L. Cannon· 1 shared C. Yang· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

T. J. Stodola

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease

J. J. VanPortfliet, Y. Lei, M. Ramanathan, C. G. Martinez, J. Wong, T. J. Stodola, B. R. Hoffmann, K. Pflug, R. Sitcheran, S. C. Kneeland, S. A. Murray, P. J. McGuire, C. L. Cannon, A. P. West

This study identifies caspase-11 as a driver of macrophage hyperinflammation in Polg-related mitochondrial disease models, linking IFN-I signaling to exacerbated infection outcomes.

bioRxiv · May 11, 2024Immunology

Methods to study xenografted human cancer in genetically diverse mice

M. G. Hasham, J. K. Sargent, M. A. Warner, S. R. Farley, B. R. Hoffmann, T. J. Stodola, C. J. Brunton, S. C. Munger

This paper describes methods to study xenografted human cancer in genetically diverse mice to better understand tumor behavior and identify suitable hosts.

bioRxiv · Jan 23, 2024 · PreprintCancer Biology

Metabolic responses of normal rat kidneys to a high salt intake.

S. Shimada, B. R. Hoffmann, C. Yang, T. Kurth, A. S. Greene, M. Liang, R. K. Dash, A. W. Cowley

This study examines how normal rat kidneys respond metabolically to a high salt diet, showing increased glycolysis and oxygen consumption despite reduced TCA cycle enzyme expression.

bioRxiv · Jan 18, 2023Physiology