Author

K. Vijayalakshmi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. G. Bassuk· 1 shared B. Ross· 1 shared C. Lenz· 1 shared E. Pilla· 1 shared G. Velez· 1 shared H. Urlaub· 1 shared J. Sengillo· 1 shared K. Wert· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. G. Bassuk

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2 papers

Recent·Most cited

Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair

M. Silva-Garcia, O. Bolgi, B. Ross, E. Pilla, K. Vijayalakshmi, M. Killisch, N. Stark, C. Lenz, M. Spitzner, M. D. Gorrell, M. Grade, H. Urlaub, M. Dobbelstein, R. Huber, R. Geiss-Friedlander

This study identifies DPP9 as a regulator of BRCA2 stability and DNA-damage repair by promoting its degradation via the N-degron pathway.

bioRxiv · Aug 24, 2020Biochemistry

Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration

K. Wert, G. Velez, K. Vijayalakshmi, V. Shankar, J. Sengillo, R. N. Zare, A. G. Bassuk, S. H. Tsang, V. B. Mahajan

The study identifies proteomic and metabolite pathways affected in retinal neurodegeneration and shows that replenishing TCA cycle metabolites provides neuroprotection.

bioRxiv · Sep 10, 2019Biochemistry