R. Huber

Discovery of anti-infective compounds against Mycobacterium marinum after biotransformation of simple natural stilbene scaffolds by a fungal secretome

This study identifies trans-δ-viniferins as promising anti-infective scaffolds against Mycobacterium marinum using a Dictyostelium discoideum infection model and natural product derivatives.

Molecular elucidation of drug-induced abnormal assemblies of the Hepatitis B Virus capsid protein by solid-state NMR

This study uses solid-state NMR to elucidate the molecular structure of drug-induced aberrant HBV capsid assemblies and reveals differences in capsid-RNA interactions and phosphorylation between in-cell and in vitro conditions.

High resolution analysis of proteolytic substrate processing

The paper develops an integrated method to analyze proteolytic substrate processing at high resolution using time-resolved mass spectrometry and other techniques.

Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair

This study identifies DPP9 as a regulator of BRCA2 stability and DNA-damage repair by promoting its degradation via the N-degron pathway.

Capturing sleep-wake cycles by using day-to-day smartphone touchscreen interactions

This study uses smartphone touchscreen interactions to measure sleep-wake cycles, finding that phone use correlates with sleep timing but overestimates sleep duration.