Author

K.-Y. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Blondel· 1 shared A. O'Brien· 1 shared A. Zettor· 1 shared C. Brearley· 1 shared C. Isel· 1 shared C.-K. C. Ding· 1 shared D. Courtney· 1 shared E. Harigua-Souiai· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Blondel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors

K.-Y. Chen, T. Krischuns, L. Ortega Varga, E. Harigua-Souiai, S. Paisant, A. Zettor, J. Chiaravalli, D. Courtney, A. O'Brien, S. Baker, C. Isel, F. Agou, Y. Jacob, A. Blondel, N. Naffakh

The paper develops a sensitive cell-based luciferase assay for high-throughput screening of SARS-CoV-2 nsp5/3CLpro inhibitors and identifies four effective compounds.

bioRxiv · Dec 18, 2021Microbiology

Mammalian stringent-like response mediated by the cytosolic NADPH phosphatase MESH1

C.-K. C. Ding, J. Rose, J. Wu, T. Sun, K.-Y. Chen, P.-H. Chen, E. Xu, S. Tian, J. Akinwuntan, Z. Guan, P. Zhou, J.-T. A. Chi

This study identifies MESH1 as a cytosolic NADPH phosphatase that promotes cell survival under ferroptosis by maintaining NADPH levels and induces transcriptional changes resembling bacterial stringent response.

bioRxiv · May 17, 2018Biochemistry

Arabidopsis inositol phosphate kinases, IPK1 and ITPK1, constitute a metabolic pathway in maintaining phosphate homeostasis

H.-F. Kuo, Y.-Y. Hsu, W.-C. Lin, K.-Y. Chen, T. Munnik, C. Brearley, T.-J. Chiou

This study identifies IPK1 and ITPK1 as key enzymes in an inositol phosphate metabolic pathway that maintains phosphate homeostasis in Arabidopsis under Pi-replete conditions.

bioRxiv · Feb 24, 2018Plant Biology