Author

Karen M. Kostroff

Northwell Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

David L. SpectoriD· 2 shared Gayatri AruniD· 2 shared Melissa KrameriD· 2 shared Sonam BhatiaiD· 2 shared William Richard McCombieiD· 2 shared Alexey S. RevenkoiD· 1 shared Disha AggarwaliD· 1 shared Fritz Joachim SedlazeckiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

David L. SpectorORCID

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Author profile →

2 papers

Recent·Most cited

Patient-derived organoid xenografts reveal the multifaceted role of the lncRNA MALAT1 in breast cancer progression

Disha Aggarwal, Suzanne Russo, Kendall L. Anderson, Taylor Floyd, Raditya Utama, James A. Rouse, Payal K. Naik, Sara A Pawlak, Shruti V. Iyer, Melissa Kramer, Shuchismita R. Satpathy, John Erby Wilkinson, Qing Gao, Sonam Bhatia, Gayatri Arun, , David L. Spector

This study evaluates MALAT1-targeting ASOs in breast cancer using patient-derived organoid models, showing MALAT1's role in alternative splicing, metastasis, and tumor-stroma interactions.

bioRxiv · Jun 27, 2026 · PreprintCancer Biology

Comprehensive analysis of structural variants in breast cancer genomes using single molecule sequencing

Sergey S. Aganezov, Sara Goodwin, Rachel M. Sherman, Fritz Joachim Sedlazeck, Gayatri Arun, Sonam Bhatia, Isac Lee, Melanie Kirsche, Robert L. Wappel, Melissa Kramer, Karen M. Kostroff, David L. Spector, Winston Timp, William Richard McCombie, Michael C. Schatz

This study uses long-read sequencing to identify structural variants in breast cancer genomes, showing high accuracy and sensitivity compared to short-read methods.

Genome Research · Sep 1, 2020Peer-reviewedBioinformatics