Raditya Utama

This study identifies PTP1B as a survival dependency in trastuzumab-resistant HER2-positive breast cancer, showing it regulates CFL1 and HSP90a abundance through dephosphorylation.

This study evaluates MALAT1-targeting ASOs in breast cancer using patient-derived organoid models, showing MALAT1's role in alternative splicing, metastasis, and tumor-stroma interactions.

This study shows that Ganaxolone inhibits PTP1B, restores TRKB/BDNF signaling, and rescues cellular morphology in CDKL5-deficient cells.

The paper shows that synonymous mutations in mycobacteria can create new transcription start sites within genes, leading to smaller protein isoforms.