A divergent mutational and clonal landscape in aged HSCs is not linked to aging-associated clonal hematopoiesis
Maria Carolina Florian, Amanda Amoah, Kalpana Nattamai, Karin Soller, Angelika Vollmer, Markus Hoenicka, Andreas Liebold, Katharina Bauer, Jan‐Philipp Mallm, Hartmut Geiger, Medhanie Assmelash Mulaw
The paper uses single-cell RNA sequencing to analyze somatic mutations in HSCs and finds age-related clonal expansion and transcriptional divergence.
bioRxiv · Jan 26, 2026 · PreprintGenomics