Control of alveolar bone development, homeostasis, and socket healing by salt inducible kinases
Nicha Tokavanich, Byron Chan, Katelyn Strauss, Christian D. Castro, Yuki Arai, Mizuki Nagata, Marc Foretz, Daniel J. Brooks, Noriaki Ono, Wanida Ono, Marc Nathan Wein
This study shows that deleting SIK2/SIK3 in alveolar bone reduces bone formation and mass by impairing osteoblast maturation, unlike in long bones where it increases bone formation and mass.
Journal of Bone and Mineral Research · Mar 6, 2025Peer-reviewedDevelopmental Biology