Author

Katja Weckmann

Max Planck Institute of Psychiatry

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Molecular Biology· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Alexandra PhilipseniD· 1 shared Bernhard KüsteriD· 1 shared Christoph W. TurckiD· 1 shared Elmira A. AnderzhanovaiD· 1 shared Felix HauschiD· 1 shared Frederik DethloffiD· 1 shared Giuseppina Maccarrone· 1 shared Jakob HartmanniD· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

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1 paper

Recent·Most cited

Stress-primed secretory autophagy drives extracellular BDNF maturation

Silvia Martinelli, Elmira A. Anderzhanova, Svenja Wiechmann, Frederik Dethloff, Katja Weckmann, Thomas Bajaj, Jakob Hartmann, Kathrin Hafner, Max L. Pöhlmann, Lee Jollans, Giuseppina Maccarrone, Felix Hausch, Christoph W. Turck, Alexandra Philipsen, Mathias V. Schmidt, , Nils C. Gassen

This study shows that stress enhances secretory autophagy via FKBP51, leading to increased MMP9 secretion and proBDNF cleavage to mature BDNF, linking stress adaptation to psychiatric disorders.

bioRxiv · May 13, 2020 · PreprintMolecular Biology