Thyroid Hormone T4 Mitigates Traumatic Brain Injury by Dynamically Remodeling Cell Type Specific Genes, Pathways, and Networks in Hippocampus and Frontal Cortex
Guanglin Zhang, Graciel Diamante, In Sook Ahn, Victoria Palafox-Sánchez, Jenny Yeuk‐Ki Cheng, Michael Cheng, Zhe Ying, Susanna Sue-Ming Wang, Kevin Daniel Abuhanna, Nguyen T. Phi, Douglas V. Arneson, Ingrid Cely, Kayla Arellano, Ning Wang, Fernando Gómez‐Pinilla, Xia Yang
This study shows T4 treatment alters cell-type specific genes, pathways, and networks in hippocampus and frontal cortex after mTBI, reversing mTBI-affected genes and pathways.
bioRxiv · Nov 15, 2022 · PreprintNeuroscience