Ingrid Cely

Trimethylamine-N-oxide affects cell type-specific pathways and networks in mouse aorta to promote atherosclerotic plaque vulnerability

This study shows TMAO affects cell type-specific pathways in mouse aorta, promoting atherosclerotic plaque instability by increasing apoptosis and reducing ECM formation.

Glo1 reduction in mice results in age- and sex-dependent metabolic dysfunction

This study shows that reducing Glo1 in mice causes age- and sex-dependent metabolic issues like obesity and altered lipid metabolism without significant changes in AGEs.

Thyroid Hormone T4 Mitigates Traumatic Brain Injury by Dynamically Remodeling Cell Type Specific Genes, Pathways, and Networks in Hippocampus and Frontal Cortex

This study shows T4 treatment alters cell-type specific genes, pathways, and networks in hippocampus and frontal cortex after mTBI, reversing mTBI-affected genes and pathways.

Cross-tissue multiomics reveals that Akkermansia muciniphila counteracts metabolic syndrome by reprograming gut microbiota, oleoylethanolamide and the gut-hypothalamus axis

This study identifies oleoylethanolamide (OEA) as a key mediator by which Akkermansia muciniphila alleviates fructose-induced metabolic syndrome through gut microbiota and gut-hypothalamus axis modulation.

Gene Networks and Pathways for Plasma Lipid Traits via Multi-tissue Multi-omics Systems Analysis

This study identifies gene networks and pathways associated with plasma lipid traits using multi-tissue multi-omics analysis, revealing both known and novel regulators of lipid metabolism.

Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to High Fructose Consumption in Mice

This study shows that gut microbiota differences between mouse strains contribute to varied metabolic responses to high fructose consumption, with Akkermansia playing a key protective role.