Trimethylamine-N-oxide affects cell type-specific pathways and networks in mouse aorta to promote atherosclerotic plaque vulnerability
Jenny Yeuk‐Ki Cheng, Michael Cheng, Satyesh K. Sinha…·Diana M. Shih
This study shows TMAO affects cell type-specific pathways in mouse aorta, promoting atherosclerotic plaque instability by increasing apoptosis and reducing ECM formation.