Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission
Ulku Cuhadar, Lorenzo Calzado-Reyes, Carlos Pascual-Caro, Aman S. Aberra, Andreas Ritzau‐Jost, Abhi Aggarwal, Keiji Ibata, Kaspar Podgorski, Michisuke Yuzaki, Christian Geis, Stefan Hallermann, Michael B. Hoppa, Jaime de Juan‐Sanz
This study shows that neuronal activity drives the translocation of LGI1 and ADAM23 to the synaptic cleft, adjusting excitatory neurotransmission based on activity history.
Cell Reports · Jan 1, 2022Peer-reviewedNeuroscience