Michael B. Hoppa

This study shows that Kv2-VAP interactions at presynaptic membrane contact sites regulate Ca2+ signaling and synaptic vesicle mobilization from the reserve pool.

The paper develops a ratiometric ER calcium sensor to enable quantitative comparisons of ER Ca2+ levels across cell types and subcellular regions, showing lower resting Ca2+ in neurons compared to fibroblasts.

This study investigates how subthreshold electric fields modulate neurotransmitter release by altering synaptic vesicle participation in presynaptic neurons.

The paper investigates the relationship between neuronal spiking frequency and FOS expression in hippocampal neurons, finding that FOS expression is cell-type specific, frequency-dependent, and not cell-autonomous.

This paper develops improved glutamate indicators with faster activation kinetics and better synaptic localization for imaging synaptic transmission in neurons.

This study shows that Kv2.1 channels form ER-PM junctions essential for ER Ca2+ uptake during neuronal activity, supporting synaptic transmission.

This study shows that neuronal activity drives the translocation of LGI1 and ADAM23 to the synaptic cleft, adjusting excitatory neurotransmission based on activity history.

The paper introduces SynTagMA, a tool to mark active synapses in a 2-second window, and provides software for analyzing large datasets of synaptic activity.

This paper demonstrates a method to use CaMPARI to label active neurons in freely-moving adult fruit flies during a stimulus.

The paper investigates the role of Kvβ1 subunits in synaptic facilitation by using optical recordings in cultured hippocampal neurons, revealing their critical role in presynaptic action potential broadening.