Author

Kelly Hodge

Cancer Research UK Scotland Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Martin BushelliD· 3 shared Sara R. ZanivaniD· 3 shared Adrianna DąbrowskaiD· 2 shared Ania WilczynskaiD· 2 shared Joseph A. WaldroniD· 2 shared June Munro· 2 shared Tobias SchmidtiD· 2 shared A.P. TurnbulliD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMolecular Biology

Martin BushellORCID

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Author profile →

3 papers

Recent·Most cited

The differential mechanisms of eIF4A1-mediated translational activation instructed by distinct RNA features

Tobias Schmidt, A.P. Turnbull, Amit Gupta, Joseph A. Waldron, Katie Pollock, June Munro, Ridvan Nepravishta, Pauline Herviou, Adrianna Dąbrowska, Kelly Hodge, Allyson M. Voelker, Leon Pang, Camila Pasquali, Georgios Kanellos, Sara R. Zanivan, , Martin Bushell

This study identifies how eIF4A1 differentially activates translation based on mRNA features, revealing distinct mechanisms for mRNA selection and inhibition by eFT226 and hippuristanol.

bioRxiv · Mar 24, 2025 · PreprintCell Biology

Purine-rich RNA sequences in the 5'UTR site-specifically regulate eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation

Tobias Schmidt, Adrianna Dąbrowska, Joseph A. Waldron, Kelly Hodge, Grigorios Koulouras, Mads Gabrielsen, June Munro, David C. Tack, Gemma Harris, Ewan James McGhee, David J. Scott, Leo M. Carlin, Danny T. C. Huang, John P. C. Le Quesne, Sara R. Zanivan, , Martin Bushell

The paper identifies AG-rich RNA sequences in 5'UTRs that regulate eIF4A1 multimerisation to enhance translation of oncogenic mRNAs.

bioRxiv · Aug 8, 2022 · PreprintMolecular Biology

Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by CDS composition and mRNA localisation

Sarah L. Gillen, Chiara Giacomelli, Kelly Hodge, Sara R. Zanivan, Martin Bushell, Ania Wilczynska

The paper investigates how the Ccr4-Not complex regulates mRNA fate and protein synthesis through codon composition, amino acid usage, and mRNA localization.

Genome biology · Oct 6, 2021Peer-reviewedMolecular Biology