Author

June Munro

Cancer Research UK Scotland Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Joseph A. WaldroniD· 4 shared Martin BushelliD· 4 shared Adrianna DąbrowskaiD· 2 shared John P. C. Le QuesneiD· 2 shared Kelly Hodge· 2 shared Louise E. MitchelliD· 2 shared Sara R. ZanivaniD· 2 shared Tobias SchmidtiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMolecular Biology

Joseph A. WaldronORCID

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Author profile →

4 papers

Recent·Most cited

The differential mechanisms of eIF4A1-mediated translational activation instructed by distinct RNA features

Tobias Schmidt, A.P. Turnbull, Amit Gupta, Joseph A. Waldron, Katie Pollock, June Munro, Ridvan Nepravishta, Pauline Herviou, Adrianna Dąbrowska, Kelly Hodge, Allyson M. Voelker, Leon Pang, Camila Pasquali, Georgios Kanellos, Sara R. Zanivan, , Martin Bushell

This study identifies how eIF4A1 differentially activates translation based on mRNA features, revealing distinct mechanisms for mRNA selection and inhibition by eFT226 and hippuristanol.

bioRxiv · Mar 24, 2025 · PreprintCell Biology

Increased mRNA translation delays lung adenocarcinoma initiation and exposes a therapeutic vulnerability to MEK inhibitors

Luis Pardo, Madeleine Moore, Ruhi S. Deshmukh, Ian R. Powley, Joseph A. Waldron, Björn Kruspig, Lynn McGarry, Colin S. Wood, Holly Leslie, Mark M. Hughes, Emanuel Jeldes, June Munro, Louise E. Mitchell, Leah Officer-Jones, Rachel L. Pennie, , Jim C. Norman

This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.

bioRxiv · Mar 19, 2025 · PreprintCancer Biology

Optimisation of sample preparation from primary mouse tissue to maintain RNA integrity for methods examining translational control

June Munro, Sarah L. Gillen, Louise E. Mitchell, Sarah Laing, Saadia A. Karim, Curtis Rink, Joseph A. Waldron, Martin Bushell

The paper optimizes sample preparation from primary mouse tissue to maintain RNA integrity for translatome analysis techniques like polysome and ribosome profiling.

Cancers · Aug 5, 2023Peer-reviewedMolecular Biology

Purine-rich RNA sequences in the 5'UTR site-specifically regulate eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation

Tobias Schmidt, Adrianna Dąbrowska, Joseph A. Waldron, Kelly Hodge, Grigorios Koulouras, Mads Gabrielsen, June Munro, David C. Tack, Gemma Harris, Ewan James McGhee, David J. Scott, Leo M. Carlin, Danny T. C. Huang, John P. C. Le Quesne, Sara R. Zanivan, , Martin Bushell

The paper identifies AG-rich RNA sequences in 5'UTRs that regulate eIF4A1 multimerisation to enhance translation of oncogenic mRNAs.

bioRxiv · Aug 8, 2022 · PreprintMolecular Biology