Author

Adrianna Dąbrowska

Cancer Research UK Scotland InstituteORCID 0000-0002-4882-5955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:machine learning (classical)· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Joseph A. WaldroniD· 2 shared June Munro· 2 shared Kelly Hodge· 2 shared Martin BushelliD· 2 shared Sara R. ZanivaniD· 2 shared Tobias SchmidtiD· 2 shared A.P. TurnbulliD· 1 shared Ahmed Saleh· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Joseph A. WaldronORCID

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Author profile →

3 papers

Recent·Most cited

The differential mechanisms of eIF4A1-mediated translational activation instructed by distinct RNA features

Tobias Schmidt, A.P. Turnbull, Amit Gupta, Joseph A. Waldron, Katie Pollock, June Munro, Ridvan Nepravishta, Pauline Herviou, Adrianna Dąbrowska, Kelly Hodge, Allyson M. Voelker, Leon Pang, Camila Pasquali, Georgios Kanellos, Sara R. Zanivan, , Martin Bushell

This study identifies how eIF4A1 differentially activates translation based on mRNA features, revealing distinct mechanisms for mRNA selection and inhibition by eFT226 and hippuristanol.

bioRxiv · Mar 24, 2025 · PreprintCell Biology

Early Prediction of Preeclampsia Based on Transposable Elements signature in cell-free RNA

Manthan Patel, Ahmed Saleh, Adrianna Dąbrowska, Fanny Boulet, Ajay K Sinha, Madapura M. Pradeepa

This study identifies a transposable element (TE) signature in maternal cell-free RNA that predicts preeclampsia with high accuracy.

bioRxiv · Nov 8, 2024 · PreprintGenomics

Purine-rich RNA sequences in the 5'UTR site-specifically regulate eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation

Tobias Schmidt, Adrianna Dąbrowska, Joseph A. Waldron, Kelly Hodge, Grigorios Koulouras, Mads Gabrielsen, June Munro, David C. Tack, Gemma Harris, Ewan James McGhee, David J. Scott, Leo M. Carlin, Danny T. C. Huang, John P. C. Le Quesne, Sara R. Zanivan, , Martin Bushell

The paper identifies AG-rich RNA sequences in 5'UTRs that regulate eIF4A1 multimerisation to enhance translation of oncogenic mRNAs.

bioRxiv · Aug 8, 2022 · PreprintMolecular Biology