Author

Kimberly L. Edwards

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amr A. AbdeeniD· 2 shared Bikash Ranjan PattnaikiD· 2 shared David M. GammiD· 2 shared Divya SinhaiD· 2 shared Krishanu SahaiD· 2 shared Pawan Kumar ShahiiD· 2 shared Alireza Fotuhi SiahpiraniiD· 1 shared Allison SpillaneiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenetics

Amr A. AbdeenORCID

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2 papers

Recent·Most cited

Nonviral base editing of KCNJ13 mutation preserves vision in an inherited retinal channelopathy

Meha Kabra, Pawan Kumar Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane, Gregory A. Newby, Shivani Saxena, Yao Tong, Yu Chang, Amr A. Abdeen, Kimberly L. Edwards, Cole O. Theisen, David R. Liu, David M. Gamm, Shaoqin Gong, , Bikash Ranjan Pattnaik

This paper demonstrates nonviral base editing of a KCNJ13 mutation in a mouse model of retinal degeneration, preserving vision through functional rescue of Kir7.1 channels.

bioRxiv · Jul 12, 2022 · PreprintGenetics

Human iPSC modeling reveals mutation-specific responses to gene therapy in Best disease

Divya Sinha, Benjamin Steyer, Pawan Kumar Shahi, Katherine P. Mueller, Rasa Valiauga, Kimberly L. Edwards, Cole Bacig, Stephanie S. Steltzer, Sandhya Srinivasan, Amr A. Abdeen, Evan Cory, Viswesh Periyasamy, Alireza Fotuhi Siahpirani, Edwin M. Stone, Budd A. Tucker, , David M. Gamm

This study uses iPSC-RPE models to evaluate gene augmentation and editing for Best disease, finding that some mutations respond to gene therapy while others require genome editing.

bioRxiv · Jan 31, 2020 · PreprintGenetics