Author

Meha Kabra

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 2 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:CRISPR screen· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Bikash Ranjan PattnaikiD· 4 shared David M. GammiD· 3 shared Krishanu SahaiD· 3 shared Amr A. AbdeeniD· 2 shared David R. LiuiD· 2 shared Divya SinhaiD· 2 shared Giovanni M. Hanstad· 2 shared Gregory A. NewbyiD· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetics

Bikash Ranjan PattnaikORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genome-Wide CRISPR Screening Identifies Cellular Factors Controlling Nonviral Genome Editing Efficiency

Shivani Saxena, Meha Kabra, Amr A. Abdeen, Diana Marcela Tabima, Divya Sinha, Piper A. Rawding, Min Zhu, Ruosen Xie, Tanvi Kulkarni, Giovanni M. Hanstad, Maria A. Fernandez Zepeda, David M. Gamm, Bikash Ranjan Pattnaik, Shaoqin Gong, Krishanu Saha

The paper uses CRISPR screening to identify genes that enhance nonviral genome editing efficiency in human cells, finding six genes that increase editing efficiency by up to five-fold.

Nature Communications · Aug 13, 2026Peer-reviewedGenomics

Prevenying vision loss in a mouse model of Leber Congenital Amaurosis by engineered tRNA

Enes Akyüz, Pawan Kumar Shahi, Lionel Gissot, Ahmad Al Saneh, Divya Sinha, Giovanni M. Hanstad, Meha Kabra, Maria A. Fernandez Zepeda, David M. Gamm, Samuel M. Young, Christopher A. Ahern, Bikash Ranjan Pattnaik

This study demonstrates that engineered tRNA can restore vision in a mouse model of Leber Congenital Amaurosis by suppressing a premature termination codon.

bioRxiv · Jul 10, 2025 · PreprintPhysiology

Nonviral base editing of KCNJ13 mutation preserves vision in an inherited retinal channelopathy

Meha Kabra, Pawan Kumar Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane, Gregory A. Newby, Shivani Saxena, Yao Tong, Yu Chang, Amr A. Abdeen, Kimberly L. Edwards, Cole O. Theisen, David R. Liu, David M. Gamm, Shaoqin Gong, , Bikash Ranjan Pattnaik

This paper demonstrates nonviral base editing of a KCNJ13 mutation in a mouse model of retinal degeneration, preserving vision through functional rescue of Kir7.1 channels.

bioRxiv · Jul 12, 2022 · PreprintGenetics

Comprehensive Analysis of CRISPR Base Editing Outcomes for Multimeric Protein

Meha Kabra, Mariya Moosajee, Gregory A. Newby, Kaivalya Molugu, Krishanu Saha, David R. Liu, Bikash Ranjan Pattnaik

The paper evaluates CRISPR base editors for correcting a KCNJ13 mutation causing LCA16, finding high on-target efficiency but negligible channel function due to bystander edits and mRNA structural issues.

bioRxiv · Jun 20, 2022 · PreprintGenetics