Author

Kristian Klindt

University of Copenhagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Celina PihliD· 2 shared Michał MarzeciD· 2 shared Muhammad Saad KhiljiiD· 2 shared Sophie Emilie BressoniD· 2 shared Tenna Holgersen BrydeiD· 2 shared Thomas R Mandrup-PoulseniD· 2 shared Björn TyrbergiD· 1 shared Carolin HoefneriD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMolecular Biology

Celina PihlORCID

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2 papers

Recent·Most cited

FK506-binding protein 2 participates in proinsulin folding

Carolin Hoefner, Tenna Holgersen Bryde, Celina Pihl, Sylvia Naiga Tiedemann, Sophie Emilie Bresson, Hajira Ahmed Hotiana, Muhammad Saad Khilji, Theodore dos Santos, Michele Puglia, Paola Pisano, Mariola Majewska, Julia Durzyńska, Kristian Klindt, Justyna E. Klusek, Marcelo Javier Perone, , Michał Marzec

This study identifies FKBP2 as a proline isomerase involved in proinsulin folding, showing its role in preventing misfolding and apoptosis in β-cells.

Biomolecules · Jan 11, 2023Peer-reviewedMolecular Biology

The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, non-toxic concentrations of interleukin 1 b

Muhammad Saad Khilji, Danielle Verstappen, Tina Dahlby, Michala Cecilie Burstein Prause, Celina Pihl, Sophie Emilie Bresson, Tenna Holgersen Bryde, Kristian Klindt, Dušan Živković, Marie‐Pierre Bousquet, Björn Tyrberg, Nils Billestrup, Thomas R Mandrup-Poulsen, Michał Marzec

The paper shows that inducible proteasomal subunits are constitutively expressed in pancreatic beta cells and upregulated by IL-1β, enhancing proteasome activity and potentially influencing autoantigen presentation.

PLoS ONE · Feb 13, 2020Peer-reviewedMolecular Biology