Author

L. A. Hohsfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Anderson· 1 shared A. Mortazavi· 1 shared A. R. Najafi· 1 shared C. Manlapaz· 1 shared C. Pachow· 1 shared C. Smith-Geater· 1 shared D. X. Figueroa Velez· 1 shared G. M. Olivarria· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Anderson

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Author profile →

2 papers

Recent·Most cited

Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice

G. M. Olivarria, Y. Cheng, C. Pachow, L. A. Hohsfield, C. Smith-Geater, R. Miramontes, J. Wu, M. S. Burns, K. I. Tsourmas, J. Stocksdale, C. Manlapaz, S. Furman, W. H. Yong, J. Teijaro, R. A. Edwards, , T. Lane

This study shows SARS-CoV-2 infects neurons in the CNS of K18-hACE2 mice, with microglia not restricting viral replication but contributing to inflammation.

bioRxiv · Nov 15, 2021Microbiology

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

L. A. Hohsfield, A. R. Najafi, Y. Ghorbanian, N. Soni, J. Crapser, D. X. Figueroa Velez, S. Jiang, S. E. Royer, S. J. Kim, A. Anderson, S. P. Gandhi, A. Mortazavi, M. A. Inlay, K. N. Green

The paper depletes adult microglia using CSF1R inhibition and shows that subventricular zone/white matter myeloid cells dynamically repopulate the brain, exhibiting distinct phenotypes from endogenous microglia.

bioRxiv · Feb 17, 2021Immunology