Author

R. McBride

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

F. G. Blankenberg· 2 shared H. Selvakumar· 2 shared J. C. Paulson· 2 shared J. D. Berry· 2 shared M. Hajfathalian· 2 shared M. Hopkins· 2 shared P. Bollyky· 2 shared T. Dharmaraj· 2 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersPharmacology & Toxicology

F. G. Blankenberg

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Author profile →

5 papers

Recent·Most cited

The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo

A. Echterhof, T. Dharmaraj, R. McBride, J. D. Berry, M. Hopkins, H. Selvakumar, K.-Y. Lin, L. Chia, C.-C. Shen, W. Lioa, P. Lee, T. Yeh, G. Suh, F. G. Blankenberg, A. Frymoyer, P. Bollyky

This study examines how neutrophils affect bacteriophage clearance and pharmacokinetics in mice, finding minimal impact from neutrophils but significant inactivation of phages over time.

JCI Insight · Oct 22, 2024Peer-reviewedPharmacology & Toxicology

Bacterial Receptors but Not Anti-Phage Defense Mechanisms Determine Host Range for a Pair of Pseudomonas aeruginosa Lytic Phages

D. M. Mueller, J. Pourtois, K. M. Kim, B. Targ, E. Burgener, C. Milla, M. Hajfathalian, H. Selvakumar, J. Berry, M. Hopkins, R. McBride, J. Antani, P. E. Turner, J. Koff, P. Bollyky

The paper identifies bacterial receptor genes determining phage host range, showing defense mechanisms are not predictive of susceptibility.

bioRxiv · Apr 30, 2024 · PreprintMicrobiology

Potential pandemic risk of circulating swine H1N2 influenza viruses

V. Le Sage, N. C. Rockey, K. R. McCarthy, A. J. French, M. J. Shephard, R. McBride, J. E. Jones, S. G. Walter, J. D. Doyle, L. Xu, D. J. Barbeau, S. Wang, S. A. Frizzell, L. H. Rigatti, M. M. Myerburg, , S. S. Lakdawala

The paper assesses the pandemic risk of swine H1N2 influenza viruses by analyzing their transmission potential and immune response in ferrets.

bioRxiv · Jan 5, 2024Microbiology

Rapid assessment of changes in phage bioactivity using dynamic light scattering

T. Dharmaraj, M. J. Kratochvil, J. D. Pourtois, Q. Chen, M. Hajfathalian, A. Hargil, Y.-H. Lin, Z. R. Evans, A. Oromi-Bosch, J. D. Berry, R. McBride, N. L. Haddock, D. R. Holman, J. D. Van Belleghem, T. H. Chang, , P. L. Bollyky

This paper uses Dynamic Light Scattering to assess phage bioactivity changes over time and optimize storage conditions for clinical phage applications.

bioRxiv · Jul 2, 2023Biophysics

Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response

L. P. Deimel, X. Xue, A. Khan, L. Moynie, C. J. Buchanan, G. Sun, R. McBride, H. Schuster, C. Gauthier, R. Saliba, K. Leonavicius, L. Minall, G. Bort, R. A. Russell, E. Sezgin, , Q. J. Sattentau

This paper shows that displaying GM3g glycans on proteins using specific chemical linkers elicits strong, germline-encoded B cell responses that do not undergo affinity maturation.

bioRxiv · Jun 3, 2023 · PreprintImmunology