Lipid droplets disrupt mechanosensing in human hepatocytes
L. Chin, N. D. Theise, A. E. Loneker, P. A. Janmey, R. G. Wells
This study shows that lipid droplets in hepatocytes disrupt mechanosensing by altering YAP nuclear localization and affecting cell spreading and focal adhesions.
bioRxiv · Mar 31, 2020Physiology