Author

L. Chiriboga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. W. Ashbrook· 2 shared B. Zeck· 2 shared C. M. Rice· 2 shared C. Quirk· 2 shared N. D. Theise· 2 shared A. F. Stenzel· 1 shared A. Lercher· 1 shared A. Ploss· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

A. W. Ashbrook

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.

A. Lercher, J.-G. Cheong, C. Jiang, H.-H. Hoffmann, A. W. Ashbrook, Y. S. Yin, C. Quirk, E. J. DeGrace, L. Chiriboga, B. R. Rosenberg, S. Z. Josefowicz, C. M. Rice

This study shows that SARS-CoV-2 infection primes alveolar macrophages for enhanced antiviral responses against influenza A virus through epigenetic changes in IFN-I pathways.

bioRxiv · Nov 24, 2023 · PreprintImmunology

Persistent hepatitis B virus and HIV coinfections in dually humanized mice engrafted with human liver and immune system

G. Hogan, B. Y. Winer, J. Ahodantin, J. Sellau, T. S. Huang, F. Douam, M. Funaki, L. Chiriboga, L. Su, A. Ploss

This study shows that dually humanized mice can support persistent HBV and HIV coinfections, enabling research on immune dysregulation and immunotherapeutic testing.

bioRxiv · May 13, 2023Microbiology

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Kabbani, E. Michailidis, S. Steensels, C. G. Fulmer, J. M. Luna, J. Le Pen, M. Tardelli, B. Razooky, I. Ricardo-Lax, C. Zou, B. Zeck, A. F. Stenzel, C. Quirk, L. Foquet, A. W. Ashbrook, , Y. P. de Jong

This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.

bioRxiv · Nov 19, 2020 · PreprintPathology

Interstitial spaces are continuous across tissue and organ boundaries in humans

O. Cenaj, D. H. R. Allison, R. Imam, B. Zeck, L. M. Drohan, L. Chiriboga, J. Llewellyn, C. Z. Liu, Y. N. Park, R. G. Wells, N. D. Theise

The paper tracks particles and hyaluronic acid to show interstitial spaces are continuous across tissue and organ boundaries in humans.

bioRxiv · Aug 7, 2020Pathology