Differential host response to a herpesvirus: Mareks disease virus peptides on chicken MHC class II molecules are derived from only a few genes and illustrate a new mode of peptide binding
S. Halabi, M. Ghosh, S. Stevanovic, H.-G. Rammensee, L. D. Bertzbach, B. B. Kaufer, M. C. Moncrieffe, B. Kaspers, S. Härtle, J. Kaufman
The paper identifies that Mareks disease virus peptides presented by chicken MHC class II molecules come from only four genes, revealing a new peptide binding mode and explaining MHC-driven resistance to the virus.
bioRxiv · Nov 27, 2020Immunology