S. Stevanovic

The Autophagy Receptor TAX1BP1 (T6BP) is a novel player in antigen presentation by MHC-II molecules.

This study identifies T6BP as a critical regulator of endogenous MHC-II antigen presentation by affecting peptide loading and CD74 stability.

Differential host response to a herpesvirus: Mareks disease virus peptides on chicken MHC class II molecules are derived from only a few genes and illustrate a new mode of peptide binding

The paper identifies that Mareks disease virus peptides presented by chicken MHC class II molecules come from only four genes, revealing a new peptide binding mode and explaining MHC-driven resistance to the virus.

Global Analysis of the Mammalian MHC class I Immunopeptidome at the Organism-Wide Scale

The paper analyzes the MHC class I immunopeptidome across human and mouse tissues, identifying tissue-specific and -independent peptide properties and hyperconserved protein sources.

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

The paper shows BTK modulates NLRP3 inflammasome activity through phosphorylation of tyrosine residues, affecting localization, oligomerization, and IL-1β release.

An innovative approach for HLA typing, molecular tumor testing and the validation of tumor exclusive antigens

The paper describes an innovative approach for HLA typing, molecular tumor testing, and validation of tumor-exclusive antigens but has been withdrawn by the authors.

Antigens in water-in-oil emulsion: a simple antigen extraction method for analysis and proof of equal antigen distribution in vaccination syringe after mixture

The paper develops a simple method to extract and analyze peptides from a water-in-oil emulsion to verify equal distribution in a vaccination syringe.

Validation of a high-performance liquid chromatography-tandem mass spectrometry immunopeptidomics assay for the identification of HLA class I ligands suitable for pharmaceutical therapies

The paper validates an LC-MS/MS immunopeptidomics assay for identifying HLA class I ligands suitable for personalized immunotherapy.

TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

The paper identifies a leucine in the K22-D35 loop of TAPBPR that facilitates peptide dissociation from MHC I, revealing distinct mechanisms for peptide editing based on the C-terminal residue in the F pocket.