Author

L. D. McCullough

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. B. Stolz· 2 shared S. Shiva· 2 shared V. A. Quaicoe· 2 shared V. R. Venna· 2 shared A. S. Mobley· 1 shared A. Sullivan· 1 shared B. Brady· 1 shared D. Green· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

D. B. Stolz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy

K. M. Dave, V. R. Venna, K. S. Rao, D. B. Stolz, B. Brady, V. A. Quaicoe, M. Maniskas, E. E. Hildebrand, D. Green, M. Chen, J. Milosevic, S.-y. Zheng, S. Shiva, L. D. McCullough, D. S. Manickam

This study compares the therapeutic efficacy of mitochondria-containing extracellular vesicles from mouse and human brain endothelial cells in a mouse stroke model, finding that mouse-derived vesicles are more effective.

bioRxiv · Jan 16, 2024 · PreprintBioengineering

ILC homeostasis phenotyping in various tissues, aging, and sex differences

A. S. Mobley, J. J. Bautista Garrido, P. Honarpisheh, J. d'Aigle, L. D. McCullough, J. Aronowski

The paper characterizes ILC homeostasis across tissues, aging, and sex using flow cytometry and proposes mathematical models to understand ILC2 subsets and markers.

bioRxiv · Dec 17, 2021 · PreprintImmunology

Mitochondria-containing EVs Protect Brain Endothelial Cells and Reduce Mouse Brain Infarct Sizes

K. Dave, D. B. Stolz, V. R. Venna, V. A. Quaicoe, M. E. Maniskas, M. J. Reynolds, R. Babidhan, D. X. Dobbins, M. N. Farinelli, A. Sullivan, T. N. Bhatia, H. Yankello, R. Reddy, Y. Bae, R. K. Leak, , D. Soundara Manickam

This paper shows that medium-to-large extracellular vesicles (m/lEVs) protect brain endothelial cells by transferring mitochondria and reducing brain infarct sizes in a mouse stroke model.

bioRxiv · Oct 29, 2021Bioengineering