Author

L. de Carvalho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Switzer· 1 shared B. C. de Jong· 1 shared B. Singha· 1 shared C. Campos· 1 shared C. J. Meehan· 1 shared C. Utpatel· 1 shared D. Brown· 1 shared D. Evangelopoulos· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. Switzer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species

E. Machado, S. Vasconcellos, L. Gomes, M. Catanho, J. Ramos, L. de Carvalho, T. Goldenberg, M. Dalcolmo, P. Redner, P. Caldas, C. Campos, M. C. Lourenco, E. Lasunskaia, V. Mussi, L. Spinasse, , P. Suffys

This study analyzes 665 Mycobacterium kansasii complex strains to identify unique and shared genomic signatures, revealing lineage splits, virulence factors, and drug resistance mechanisms.

bioRxiv · Feb 14, 2024Evolutionary Biology

Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosis

M. Khan, D. M. Hunt, B. Singha, Y. Kapoor, N. Singh, D. V. S. Prasad, S. Dharmarajan, D. T. Sowpati, L. de Carvalho, V. K. Nandicoori

The paper identifies two non-canonical L-cysteine synthases in Mtb, CysM and CysK2, which support divergent biosynthetic pathways critical for redox stress response and survival during infection.

bioRxiv · Oct 3, 2023Microbiology

A role for a conserved kinase in the transcriptional control of methionine biosynthesis in Escherichia coli experiencing sustained nitrogen starvation

A. Switzer, D. Evangelopoulos, R. Figueira, L. de Carvalho, D. Brown, S. Wigneshweraraj

This study identifies YeaG as a kinase that regulates methionine biosynthesis in E. coli under sustained nitrogen starvation by modulating the activity of the transcriptional repressor MetJ.

bioRxiv · Jan 27, 2018Microbiology