Author

C. Utpatel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:whole-genome sequencing· 5 Organism:human· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. Niemann· 5 shared A. Spitaleri· 2 shared L. Rigouts· 2 shared A. Barbova· 1 shared A. Cabibbe· 1 shared A. Dean· 1 shared A. Sanchini· 1 shared A. Skrahina· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMicrobiology

S. Niemann

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species

E. Machado, S. Vasconcellos, L. Gomes, M. Catanho, J. Ramos, L. de Carvalho, T. Goldenberg, M. Dalcolmo, P. Redner, P. Caldas, C. Campos, M. C. Lourenco, E. Lasunskaia, V. Mussi, L. Spinasse, , P. Suffys

This study analyzes 665 Mycobacterium kansasii complex strains to identify unique and shared genomic signatures, revealing lineage splits, virulence factors, and drug resistance mechanisms.

bioRxiv · Feb 14, 2024Evolutionary Biology

Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity

J. Botelho, L. Tüffers, J. Fuss, F. Buchholz, C. Utpatel, J. Klockgether, S. Niemann, B. Tümmler, H. Schulenburg

This study examines phylogroup-specific evolutionary dynamics in Pseudomonas aeruginosa genomes, revealing distinct pangenome characteristics and distribution patterns of antimicrobial resistance genes and defence systems.

bioRxiv · Apr 24, 2022Microbiology

Deciphering Bedaquiline and Clofazimine Resistance in Tuberculosis: An Evolutionary Medicine Approach

L. Sonnenkalb, J. Carter, A. Spitaleri, Z. Iqbal, M. Hunt, K. Malone, C. Utpatel, D. M. Cirillo, C. Rodrigues, K. S. Nilgiriwala, the CRyPTIC Consortium, P. W. Fowler, M. Merker, S. Niemann

This study identifies 230 genomic variants associated with resistance to bedaquiline and clofazimine in tuberculosis using experimental evolution, genome sequencing, and structural modeling.

bioRxiv · Mar 19, 2021Microbiology

Improving tuberculosis surveillance by detecting international transmission using publicly available whole-genome sequencing data

A. Sanchini, C. Jandrasits, J. Tembrockhaus, T. A. Kohl, C. Utpatel, F. P. Maurer, S. Niemann, W. Haas, B. Y. Renard, S. Kroeger

This study uses global whole-genome sequencing data to identify international tuberculosis transmission clusters, improving surveillance by connecting cases across countries.

Eurosurveillance · Jan 14, 2021Peer-reviewedMicrobiology

Characterization of genomic variants associated with resistance to bedaquiline and delamanid in naïve Mycobacterium tuberculosis clinical strains

S. Battaglia, A. Spitaleri, A. Cabibbe, C. Meehan, C. Utpatel, N. Ismail, S. Tahseen, A. Skrahina, N. Alikhanova, K. S. Mostofa, A. Barbova, S. Niemann, R. Groenheit, A. Dean, M. Zignol, , D. Cirillo

This study identifies genetic mutations associated with resistance to bedaquiline and delamanid in Mycobacterium tuberculosis strains using whole genome sequencing and in silico analysis.

bioRxiv · May 27, 2020Microbiology